Revised MAY 2021
  • Primary authorship shared by lab members


  • DNA methylation and gene expression patterns are widely altered in fetal growth restriction and associated with FGR development

Seoyeong Lee, Young Nam Kim, DoHwa Im, Su Han Cho, Jiyeon Kim, Jeong-Hyun Kim, Kwoneel Kim. Animal Cells and Systems.


  • Accelerated evolution of the regulatory sequences of brain development in the human genome

Kang Seon Lee, Hyoeun Bang, Jung Kyoon Choi, Kwoneel Kim. Molecules and Cells.

  • How to interpret and integrate multi-omics data at systems level

Gun Tae Jung, Kwang-Pyo Kim, Kwoneel Kim. Animal Cells and Systems.

  • Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity

Kwoneel Kim, Hong Sook Kim, Jeong Yeon Kim, Hyunchul Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Se-Hoon Lee, Jung Kyoon Choi. Nature Communications.


  • Network perturbation by recurrent regulatory variants in cancer.

Kiwon Jang, Kwoneel Kim, Ara Cho, Insuk Lee, Jung Kyoon Choi. PLoS Computional Biology.


  • Chromatin structure-based prediction of recurring noncoding mutations in cancer.

Kwoneel Kim, Kiwon Jang, Woojin Yang, Eun-Young Choi, Seong-Min Park, Mingyun Bae, Youn-Jae Kim & Jung Kyoon Choi. Nature Genetics.

  • Intersection of genetics and epigenetics in monozygotic twin genomes.

Kwoneel Kim, Kibaick Lee, Hyoeun Bang, Jeong Yeon Kim, Jung Kyoon Choi. Methods.


  • Global transcription network incorporating distal regulator binding reveals selective cooperation of cancer drivers and risk genes.

Kwoneel Kim, Woojin Yang, Kang Seon Lee, Hyoeun Bang, Kiwon Jang, Sang Cheol Kim, Jin Ok Yang, Seongjin Park, Kiejung Park and Jung Kyoon Choi. Nucleic Acids Research.

  • Genetic architecture of transcription and chromatin regulation.

Kwoneel Kim, Hyoeun Bang, Kibaick Lee, Jung Kyoon Choi. Genomics & Informatics.


  • Genetic factors underlying discordance in chromatin accessibility between monozygotic twins.

Kwoneel Kim, Hyo-Jeong Ban, Jungmin Seo, Kibaick Lee, Maryam Yavartanoo, Sang Cheol Kim, Kiejung Park, Seong Beom Cho and Jung Kyoon Choi. Genome Biology.

  • Collagen Triple Helix Repeat Containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells.

Hee Cheol Kim3, Yong Sung Kim, Hyun-Woo Oh, Kwoneel Kim, Sang-Seok Oh, Jong-Tae Kim, Bo Yeon Kim, Seon-Jin Lee, Yong-Kyung Choe, Dong Hyeok Kim, Seok-Hyung Kim, Seoung Wan Chae, Kwang Dong Kim, and Hee Gu Lee. Oncotarget.


  • Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation.

Jungmin Seo, Kwoneel Kim, Dong-Yeop Chang, Ho-Bum Kang, Eui-Cheol Shin, Jongbum Kwon and Jung Kyoon Choi. Nucleic Acids Research.

  • Regulation of the boundaries of accessible chromatin.

Xiaoran Chai, Sanjanaa Nagarajan, Kwoneel Kim, Kibaick Lee, Jung Kyoon Choi. PLoS Genetics.

  • Genetic landscape of open chromatin in yeast.

Kibaick Lee, Sang Cheol Kim, Inkyung Jung, Kwoneel Kim, Jungmin Seo, Heun-Sik Lee, Gireesh K. Bogu, Dongsup Kim, Sanghyuk Lee, Byungwook Lee, Jung Kyoon Choi. PLoS Genetics.


  • Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer.

Kwoneel Kim, Han-Chul Lee, Jong-Lyul Park, Mirang Kim, Seon-Young Kim, Seung-Moo Noh, Kyu-Sang Song, Jin Cheon Kim and Yong Sung Kim. Epigenetics.